Biological Mechanisms of PRP in Vaginal Tissue Restoration

Vaginal tissue integrity is maintained through complex interactions between vascular supply, extracellular matrix structure, and cellular turnover. PRP therapy addresses these mechanisms directly by delivering a high concentration of autologous growth factors to targeted tissues.

Once activated, PRP releases platelet-derived growth factor (PDGF), transforming growth factor-beta (TGF-β), and vascular endothelial growth factor (VEGF), all of which contribute to enhanced microcirculation and collagen synthesis. These effects result in progressive tissue strengthening rather than temporary symptom relief.

From an academic perspective, PRP represents a shift from hormonal modulation to biological regeneration. CE Marked Class IIb PRP systems achieving platelet counts above 4 million ensure standardized outcomes suitable for clinical protocols and academic training.

PRP-based vaginal regeneration reflects the evolution of gynecology toward regenerative and preventive medicine.